TGFβ1 and TGFβ3 are partially redundant effectors in brain vascular morphogenesis
نویسندگان
چکیده
منابع مشابه
TGFβ1 and TGFβ3 are partially redundant effectors in brain vascular morphogenesis
Gene deletion experiments have shown that the three TGFbeta isoforms regulate distinct developmental processes. Recent work by our group and others showed that the integrins alphavbeta6 and alphavbeta8 activate latent forms of TGFbeta1 and TGFbeta3. This raises the possibility that TGFbeta1 and TGFbeta3 act redundantly in developmental processes where both isoforms are expressed and activation ...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2008
ISSN: 0925-4773
DOI: 10.1016/j.mod.2008.01.003